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Tamas Horvath

 

Neuroscience

Chair and Professor of Comparative Medicine
Professor of Neurobiology and Obstetrics & Gynecology

Education

D.V.M. University of Veterinary Sciences, Hungary 1990
Ph.D. Szeged University, Hungary 1999

Research Interests

My main interest is the neuroendocrine regulation of homeostasis with particular emphasis on metabolic disorders, such as obesity and diabetes, and the effect of metabolic signals on higher brain functions and neurodegeneration. We have active research programs to pursue the role of synaptic plasticity in the mediation of peripheral hormones’ effects on the central nervous system. We also study the role of mitochondrial membrane potential in normal and pathological brain functions with particular emphasis on the acute effect of mitochondria in neuronal transmission and neuroprotection. We combine classical neurobiological approaches, including electrophysiology and neuroanatomy, with endocrine and genetic techniques to better understand biological events at the level of the organism.

Recent Publications

• Gao, Q., et al. (2007). Anorectic estrogen mimics leptin’s effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat. Med. 13(1):89-94.
• Coppola, A., et al. (2007). A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. Cell Metab. 5(1):21-33.

Contact

E-mail
tamas.horvath@yale.edu