Fred J. Sigworth
CURRICULUM VITAE |
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| Born |
October 20, 1951 in Berkeley, California |
| Education |
Stanford University (1969-1971), Electrical Engineering
California Institute of Technology (1971-1974), Applied Physics. Concentrated on semiconductor physics with Professor C.A. Mead as advisor. Received B.S. with honor, 1974.
Graduate study at the University of Washington (1974-1975) and at Yale University (1975-1979) under C.F. Stevens, working on conductance fluctuations in nerve membrane. Received Ph.D. from Yale in 1979.
Post-Doctoral Fellow of the Alexander von Humboldt Stiftung (1979-1981), and continued as a Research Associate (1981-1984) in the laboratory of E. Neher at the Max Planck Institute for Biophysical Chemistry, Göttingen, Germany. |
| Present position |
Professor, Department of Cellular and Molecular Physiology, Yale University School of Medicine. Member of the faculty since December, 1984. |
| Honors |
Alexander von Humboldt Fellow, 1979-1981
Jacob Javits Neuroscience Investigator Award, 1992
Yale Science and Engineering Award, 1996
K. C. Cole Award, Biophysical Society, 1997
Bohmfalk Teaching Prize, Yale School of Medicine, 2002.
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| Other experience |
Chairman, 1994 Gordon Conference on Ion Channels
Editorial Boards, Neuron, Journal of General Physiology, European Biophysics Journal.
Invited lecturer in the Shanghai Ion Channel Workshop, 1987; Ion Channels course at Cold Spring Harbor Laboratory, 1990-1994. Invited lecturer in the Computational Neuroscience course 1994-7 and the Neurobiology Course, 1996-2003 at the Marine Biological Laboratory. |
| Research interests |
My main interest has been in the areas of gating and ion permeation in the ionic channels of excitable cell membranes, and how the structure of channel proteins give rise to these properties. The approach in my laboratory has been to develop new electronic and computer techniques for sensitive electrical measurements of ion channel currents, and to apply these techniques along with biochemical and molecular biology tools to the study of the function of ion channel proteins. More recently, my laboratory has been working on structural studies of ion channels using high-resolution electron microscopy.
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