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Information About Research Projects for Heavy Drinkers and Healthy
People
Heavy Drinkers
CTNA offers a variety
of research programs designed to help people control their drinking while
providing important information about brain mechanisms related to drinking
behaviors. Some of the programs offer "inpatient detoxification"
(4 weeks of medical and psychological support toward abstinence) with
testing during and after the detoxification period. Some programs include
people who continue to drink (not seeking treatment) during testing.
Please call (telephone
numbers listed below) or email the Alcohol Research Center at: ARC1@yale.edu
| Heavy
Drinkers who want inpatient treatment |
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Contact |
203-937-4788, Elizabeth.Guidone@yale.edu |
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Studies: |
MRS, MRI and
PET scans of the brain; includes 30 days of free detox treatment
in hospital. Participants are referred to an outpatient program
upon discharge. Eligibility: ages 18 - 60, alcohol abuser, not currently
taking medication for a psychiatric problem. In addition to free
treatment, participants will be paid. Earnings can range from $350
to $1,000 or more, depending on the number of studies enrolled in.
HIC#25975, 12179,
9238; HSS# JK00569, JK0058, JS02
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| Heavy
Drinkers who want outpatient treatment |
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Contact |
203-932-5711
ext. 5217, Diana |
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Study |
4 test days
taking one dose of medication each day. Eligibility: ages 21-60,
alcohol abuser, medically healthy, no psychiatric disorder. In addition
to free treatment, participants will be paid $150 for each test
day they complete.
HIC#12449, HSS
JK41
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| Formerly
Heavy Drinkers (sober for 1 month or longer) |
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Contact |
203-937-4788,
Elizabeth.Guidone@yale.edu |
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Study |
MRS, MRI and
PET scans of the brain. Eligibility: ages 18 - 60, prior treatment
for alcohol abuse, not currently taking medication for a psychiatric
problem, sober for one month or longer. Participants will be paid.
Earnings can range from $150 to $1,000 or more, depending on the
number of studies enrolled in
HIC 25975, 12179,
9238, HSS# JK00569, JK0058, JS02
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| Heavy
Drinkers who do NOT want treatment |
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Contact |
203-974-7679, Nicholas.Franco@yale.edu |
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Study |
Three appointments,
followed by 6 days of medication with memantine and one 24-hour
stay in Yale New Haven Hospital. Eligibility: Healthy adults, ages
21 - 50, heavy drinkers (Minimum: men 25 drinks per week, women
20 drinks per week), not taking medication for a psychiatric problem,
not using opiates. Participants will be paid and can earn up to
$676.
HIC# 0602001068
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Heavy
Drinkers who Want Inpatient Treatment (Or are Currently Enrolled in a Detox
Program):
Contact: (203) 932-5711 Ext: 2593
Study: ERP and fMRI
scans of the brain, cognitive testing, follow-up session; includes free
21 day detox program in the hospital. Eligibility: Alcohol abusers with
no history of dependence on other substances (except nicotine). No abuse
of substances other than alcohol within one year of study. No history
of major medical, neurological, or psychiatric conditions. No metallic
objects in body. The study consists of 5 sessions: 1) Screening, 2) ERP,
3) fMRI, 4) Cognitive Assessment, and 5) 3 Month Follow Up. In addition
to free treatment, participants will be paid up to $215 for completion
of the study.
Yale HIC# 12195,
VA IRB# DM0002
Former
Heavy Drinkers (Sober for at least 1 year):
Contact: (203) 932-5711 Ext: 2593
Study: ERP and fMRI
scans of the brain, cognitive testing, Eligibility: Former alcohol abusers
who have been sober for at least 1 year. No history of dependence on other
substances (except nicotine). No abuse of any substance within one year
of study. No history of major medical, neurological, or psychiatric conditions.
No metallic objects in body. The study consists of 5 sessions: 1) Screening,
2) ERP, 3) fMRI, 4) Cognitive Assessment, and 5) 3 Month Follow Up. Participants
will be paid up to $215 for completion of the study.
Yale HIC# 12195,
VA IRB# DM0002
Heavy Drinking Young Adults: Contact:
203-974-7373
Study: Naltrexone
taken on a targeted (as needed) basis over the course of 2 months, physical
exam/lab work, biweekly assessment appointments, daily questionnaires.
Eligibility: Healthy young adults ages 18-25 drinking at least 2 days
per week on average.
In addition to free medication and lab work, qualified participants will
be compensated up to $295.
Yale HIC # 0511000768
Healthy
Males (Light Drinkers and Non-Drinkers): Contact: (203) 932-5711
Ext: 2593
Study: Screening session, ERP brain wave recording, Eligibility: Healthy
adult males between 33-37 years old or 50-54 years old. No history of dependence
on any substances (except nicotine). No abuse of any substance within one
year of study. No history of major medical, neurological, or psychiatric
conditions. The study consists of a screening session (approx. 1-2 hours)
and an ERP session (approx. 2 hours). Participants will be paid by the hour
(an approximate total of $60).
HIC# 17234, VA IRB#
DM0007
Healthy People (with or without a family history of alcoholism)
CTNA also has studies
that examine the biological and genetic basis of alcoholism. We need people
who are not heavy drinkers but have a family member who drinks heavily
to participate in projects. Some of the programs focus on differences
between families with and without heavy drinkers.
| Light
Drinkers healthy people, with or without a family history of alcoholism,
arc1@yale.edu |
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Contact |
203-932-5711 ext. 5688 on weekdays, or 203-843-7031 after business hours |
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Study |
3 test days
taking one dose of medication each day. Eligibility: ages 21-30,
healthy, with or without a family history of alcoholism. No psychiatric
disorder, Mother not heavy drinker. Participants will be paid $150
for each test day they complete.
HIC#12449; HSS
IPO17, IPO22
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| Non-Drinkers
(abstinent) and Light Drinkers healthy people, with or without a family
history of alcoholism |
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Contact |
203-937-4788 |
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Study |
MRS scans of the brain. Eligibility: ages 18 - 60, not currently
taking medication for a psychiatric problem; never had a problem
with drugs or alcohol. Participants will be paid. Earnings can range
from $150 to $600 or more, depending on the number of studies
enrolled in.
HIC#25975, 12179; HSS
0062, 0058
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