 |
 |
 |
 |
 |
 |
 |
|
|||||||||
|
|
|
|||||||
|
|
|
|||||||
|
|
|
|||||||
|
 |
CTNA Publications (updated April 2005)Abi-Saab W, Cavus I, Spencer D, Sherwin R, Krystal J. Insights into the relationship between excitatory neurotransmission, energy substrates, and function in the human hippocampus: insights from intracortical microdialysis and electrophysiologic studies in awake epileptic patients. Biol Psychiatry 2002;51:159S (#468) Abi-Saab W, Maggs DG, Jones T, Jacob R, Srihari V, Thompson J, Kerr D, Leone P, During MJ, Krystal JH, Spencer D, Sherwin RS. Striking differences in glucose and lactate concentrations in brain extracellular fluid and plasma in conscious human subjects. J Cereb Blood Flow Metab 2002;22(3):271-279 Anand A, Moghaddam B, Krystal JH. Effects of NMDAR antagonists: implications for schizophrenia-reply. Arch Gen Psychiatry 2002;59:663-664 Balogh, S.A. , Keller, J.J., Picciotto, M. R., Paylor, R., Booker, T.K., Beaudet, A., Heinemann, S. and Wehner, J.M. (2004) Role of neuronal nicotinic receptors in the effects of nicotine and ethanol on contextual fear conditioning. Submitted. Barnett, N.P., Fromme, K., Corbin, W., Borsari, B., Carey, K.B., Colby, S.M., & Monti, P.M. Brief alcohol interventions with mandated or adjudicated college students. Alcoholism: Clinical and Experimental Research, (submitted) Basu D, Ball SA, Feinn R, Gelernter J, and Kranzler HR: Typologies of Drug Dependence: Comparative Validity of a Multivariate and Four Univariate Models. In press, Drug & Alcohol Dependence Belger A, Fermaglich L, Vita L, Gore JC, Krystal JH. Event-related functional magnetic resonance imaging of neural networks underlying cognitive interference. Human Brain Mapping in revision. Blumberg HP, Kaufman J, Martin A, Whiteman R, Gore JC, Charney DS, Krystal JH, Peterson BS. Amygdala and hippocampus volumes in adolescents and adults with bipolar disorder. Arch Gen Psychiatry 2003;60:1201-1208 Blumberg HP, Leung HC, Skudlarski P, Lacadie CM, Fredericks C, Harris BC, Charney DS, Gore JC, Krystal JH, Peterson BS. A functional magnetic resonance imaging study of bipolar disorder: State- and trait-related dysfunction in ventral prefrontal cortices. Arch Gen Psychiatry 2003;60:601-609 Blumberg HP, Martin A, Kaufman J, Leung H-C, Skudlarski P, Lacadie C, Fulbright R, Gore JC, Charney DS, Krystal JH, Peterson BS. Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations using functional MRI. Am J Psychiatry 2003;160:1345-1347 Chambers RA, Potenza MN, Hoffman RE, Miranker W. Simulated apoptosis/neurogenesis regulates learning and memory of adaptive multilayer neural networks. Neuropsychopharmacol (in press) http://www.acnp.org/citations/NPP10230303327/default.pdf Cavus I, Abi-Saab WM, Zavery H, Cassaday M, Spencer DD, Sherwin RS, Krystal J. Cognitive stimulation increases extracellular glutamate, glucose, and lactate levels and modulates theta activity. A microdialysis and hippocampal depth electrode study in awake behaving humans. Biol Psychiatry 2002;51:160S (#469) Corbin, W.R., Roth, J., & Fromme, K. Stimulant alcohol effects prime loss of control drinking. Experimental and Clinical Psychopharmacology.(submitted) Covault J, Gelernter J, Hesselbrock V, Nellissery M, Kranzler HR: Allelic and haplotypic association of GABRA2 with alcohol dependence. Am J Med Genet. 2004;129B:104-109 Cramer J, Rosenheck R, Kirk G, Krol W, Krystal JH (and the VA Naltrexone Study Group 425). Usefulness of a compliance feedback and monitoring program in a multicenter treatment trial. Value in Health 2003; 6: 566-573. Daurignac E., Krishnan-Sarin S., OMalley S.S., Krystal J.H., Ford J.M., Mathalon D.H. Effects of family history and gender on P300 in alcohol dependence. Abstract RSA 2004. Desai RA, Maciejewski PK, Dausey DJ, Caldarone BJ, Potenza MN Health correlates of recreational gambling in older adults. Am J Psychiatry(in press) D'Souza DC, Gil R, MacDougall L, Cassello K, Boutros N, Innis RB, Krystal JH. GABA serotonin interactions in healthy subjects: implications for psychosis and dissociation. Neuropsychopharmacology in revision. Epperson CN, Mason GF, Haga K, Appel M, Sellers E, Gueorguieva R, Rothman D, Krystal JH. Differential menstrual cycle-related fluctuations in cortical??-aminobutyric acid levels in women with premenstrual dysphoric disorder (PMDD) and healthy menstruating women: a 1H-MRS study.Arch Gen Psychiatry 2002;59:851-858 Epperson CN, O'Malley S, Czarkowski K, Gueorguieva R, Rothman DL, Sanacora G, Krystal JH, Mason GP. Sex, GABA, and nicotine: the impact of smoking and menstrual cycle phase on cortical GABA levels measured with 1H-MRS. Biol Psychiatry in review. Epperson CN, Cappiello A, Czarkowski K, Stiklus S, Wasylink S, Anderson G, Heninger G, Charney DS, Krystal JH. Effects of estrogen on depressive relapse after tryptophan depletion in remitted depressed menopausal women. In review First, MB, Bell C, Cuthbert B, Krystal J, Malison R, Offord D, Reiss D, Shea T, Widiger T, Wisner K. Personality disorders and relational disorders: a research agenda for addressing crucial gaps in DSM. APA Research Agenda for DSM-V. Kupfer DJ, First MB, Regier DA (eds), American Psychiatric Association: Washington, D.C., 2002;123-199 Fromme, K. & Corbin, W.R. Prevention of heavy drinking and associated negative consequences among mandated and voluntary college students. Journal of Consulting and Clinical Psychology. (In Press). Fromme, K., deWit, H., Hutchinson, K.E., Ray, L., Corbin, W.R., Cook, T.A., Wall, T.L., & Goldman, D. Biological and behavioral markers of alcohol sensitivity. Alcoholism: Clinical and Experimental Research. (In Press). Gelernter J, Liu X, Hesselbrock V, Page GP, Goddard A, and Zhang H: Results of a genomewide linkage scan: Support for chromosomes 9 and 11 loci increasing risk for cigarette smoking. In press, Am J Med Genet (Neuropsych Genet) 2004;128B, 94-101 Gelernter J, Page GP, Stein MB, and Woods SW: Genomewide linkage scan for loci predisposing to social phobia: evidence for a chromosome 16 risk locus. In press, American Journal of Psychiatry Goddard AW, Mason G, Rothman DL, Behar KL, Krystal JH. Influence of medication and family history on cortical GABA levels in panic disorder. Biol Psychiatry 2002;51:48S (#143) Goddard AW, Mason GF, Rothman DL, Behar KL, Krystal JH. Reduced cortical GABA neuronal response to benzodiazepine administration in panic disorder. Am J Psychiatry in press Gueorguieva R, Krystal JH. Move over ANOVA: Progress in analytic methods for repeated measures data from psychiatric clinical trials. Arch Gen Psychiatry in revision. Jacobsen LK, Gore JC, Skudlarski P, Lacadie CM, Jatlow P, Krystal JH: Impact of intravenous nicotine on BOLD signal response to photic stimulation, Magnetic Resonance Imaging 2002;20:141-145 Jacobsen LK, Pugh KR, Mencl WE, Skudlarksi P, Krystal JH. Preliminary evidence of hippocampal dysfunction in adolescent MDMA ('Ecstasy') users: possible relationship to neurotoxic effects. Psychopharmacology In press. Jacobsen LK, Krystal JH, Mencl WE, Westerveld M, Frost SJ, Pugh KR. Effects of smoking and smoking abstinence on cognition in adolescent tobacco smokers. In review. Kaufman J, Yang B-Z, Douglas-Palumberi H, Houshyar S, Lipschitz D, Krystal JH, Gelernter J. Social supports and serotonin transporter gene moderate depression in maltreated children. Proc Nat Acad Sci USA In press. Krishnan-Sarin S, George TP, O'Connor PG, O'Malley S. HPA axis responsivity: differential changes produced by alcohol and/or nicotine dependence. in symposium: Stress-Axis Reactivity to Pharmacologic Challenges: Defining the Disruption in the Drinkers and their Kids. Abstract RSA 2004 Krishnan-Sarin, S., Shi, J., M.D., Reutenauer, E., B.S., Bathey, S., Grant, C., Thoni, S., Zhang, J., Krystal, J., O'Malley, S. Individual differences in alcohol self-administration behavior. Symposium at RSA 2004 Krishnan-Sarin, S., Shi, J., Duhig, A., Cramer, J., Zhang, J., Krystal, J., O'Malley, S.S. Response in the Color-Word Stroop task: Influence of Family history of alcoholism, alcohol administration and Naltrexone. Poster at RSA 2004 Krystal J. Detoxification and Initiation of Abstinence from Alcohol Comparing Gabapentin, Valproic Acid and Placebo Augmentation of Benzodiazepine Escape. Alc Clin Exp Res 2003; 27(5); 148A (#857) Krystal JH, Abi-Saab W, Perry E, D'Souza DC, Liu N, McDougall L, Belger A, Levine L, Breier. Modulation of ketamine-induced working memory deficits in healthy human subjects by the group II metabotropic agonist, LY354740. American College of Neuropsychopharmacology, 41th Annual Meeting, San Juan, Puerto Rico, December 9-13, 2002 abstract Krystal JH, Abi-Saab W, Perry E, D'Souza DC, Liu N, Gueorguieve R, McDougall L, Hunsberger T, Belger A, Levine L, Breier A. Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the the group II metabotropic glutamate receptor (mGluR) agonist, LY354740, in healthy human subjects. Psychopharmacology in press. Krystal JH, Cramer JA, Rosenheck R, and the VA Naltrexone Study Group 425. What predicts response to treatment? Alc Clin Exp Res 2002;26(5):86A (#487) Krystal JH, Petrakis I, Limoncelli D, Webb E, Gueorgueva R, D'Souza DC, Boutros NN, Trevisan L, Charney DS. Altered NMDA Glutamate Receptor Antagonist Response in Recovering Ethanol Dependent Patients. Alc Clin Exp Res 2003; 27(5); 19A (#79) Krystal JH, Petrakis I, Limoncelli D, Webb E, Gueorgueva R, Trevisan L, Boutros NN, D'Souza DC. Impact of Family Alcohol Dependence History Upon NMDA Receptor Function in Recovering Alcohol Dependent Patients. Alc Clin Exp Res 2003; 27(5); 46A (#246) Krystal JH, Petrakis IL, Krupitsky E, Schütz C, Trevisan L, D'Souza DC. NMDA Receptor Antagonism and the Ethanol Intoxication Signal: From Alcoholism Risk to Pharmacotherapy. Ann NY Acad Sci, 2003; 1003: 176-184. Krystal JH, Petrakis IL, Limoncelli D, Webb E, Gueorgueva R, D'Souza DC, Boutros N, Trevisan L, Charney DS. Altered NMDA glutamate receptor antagonist response in recovering ethanol dependent men. Neuropsychopharmacology 2003;28:2020-2028 Krystal JH, Petrakis IL, Mason G, D'Souza DC. NMDA glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability. Pharmacol Therapeutics in press. Krystal JH, Petrakis IL, Mason G, Trevisan L, D'Souza DC. NMDA Glutamate Receptors and Alcoholism: Reward, Dependence, Treatment, and Vulnerability. Pharmacology & Therapeutics 99, 2003; 79-94. Krystal JH, Petrakis IL, Trevisan L, D'Souza DC. NMDA receptor antagonism and the ethanol intoxication signal: From alcoholism risk to pharmacotherapy. Annals NY Academy of Science, in press. Krystal JH, Rosenheck R, Cramer J, and the VA Naltrexone Study Group 425. Relapse to heavy drinking during and after treatment in the VA mulicenter naltrexone trial. Alc Clin Exp Res 2002;26(5):86A (#486) Krystal JH, Sanacora G, Blumberg H, Anand, A, Charney DS, Marek G, Epperson CN, Goddard A, Mason GF. Glutamate and GABA systems as targets for novel antidepressant and mood stabilizing treatments. Mol Psychiatry 2002;7:S71-S80 Krystal JH. First, do no harm; then, do some good: ethics and human psychopharmacology. Israel Journal of Psychiatry and Related Sciences 2002;39(2):89-91 Krystal, JH., Petrakis, IL., D'Souza, D. C., Mason, G., Trevisan, L. Alcohol and glutamate neurotransmission in humans: implications for reward, dependence, and treatment. In: Glutamate and addiction. Herman BH, Frankenheim J, Litten RZ, Sheridan PH, Weight FF, Zukin SR (eds), Totowa, NY: Humana Press, 2002; in press. Lappalainen J, Kranzler HR, Malison R, Price LH, Van Dyck C, Rosenheck
RA, Cramer J, Southwick SM, Charney DS, Krystal JH, Gelernter J. A functional
neuropeptide Y Leu7Pro polymorphism is associated with alcohol dependence
in a large American population sample. Arch Gen Psychiatry 2002;59:825-831 Lappalainen J, Kranzler HR, Petrakis IL, Somberg LK, Page G, Krystal JH, Gelertner, J. Confirmation and Fine-Mapping of the Chromosome 1 Alcohol Dependence Risk Locus, Molecular Psychiatry, in press. Lappalainen J, Krupitsky E, Remizov M, Pchelina S, Taraskina A, Zvartau E Somberg LK, Covault J, Kranzler HR, Krystal JH, and Gelernter J: Association between alcoholism and GABRA2 in a Russian population. Alc Clin Exp Res (in press) Lappalainen J, Sanacora G, Kranzler HR, Malison R, Hibbard ES, Price LH, Krystal JH, Gelernter J. Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression. Neuropsychiatric Genetics in press. Luo X, Kranzler HR, Zhao H, and Gelernter J: Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European Americans. Am J Med Genet (Neuropsych Genet) 120B:97 108, 2003 Mason GF, Appel M, de Graaf RA, Petrakis I, Ruff E, Rothman DL, Krystal JH (2003) Brain GABA falls by 1 month of detoxification and remains low. Research Society on Alcoholism (in press : June 2003) -- oral presentation Mason GF, Appel M, de Graaf RA, Petrakis I, Ruff E, Rothman DL, Krystal JH (2003) Brain GABA falls by 1 month of detoxification and remains low. Alc Clin Exp Res 2004: 27:48A. Mason GF, Appel M, de Graaf RA, Ruff E, Rothman DL, Krystal JH (2003) Brain GABA falls with sobriety in alcohol-dependent subjects. Proceedings of the International Society of Magnetic Resonance in Medicine (in press : May 2003) -- oral presentation Mason GF, Petrakis IL, de Graaf RA, Appel M, Gueorguieva R, Ruff E, Coric V, Epperson CN, Rothman DL, Krystal JH. Cortical GABA levels and the recovery from alcohol dependence: relationship to neurotoxicity and cigarette smoking. In Review. Mason GF, Appel M, de Graaf RA, Petrakis I, Ruff E, Rothman DL, Krystal JH, Reduction in Cortical GABA Levels Over the First Month of Sobriety. Alc Clin Exp Res 2003; 27(5); 56A (#305) Mason GF, Petrakis IL, Haga K, Frisbee R, Appel M, Rothman DL, Krystal JH. Preliminary evidence of decreased cortical GABA in patients during alcohol detoxification. Alc Clin Exp Res 2002;26(5):105A (#599) Mason GF, Sibson NR, Behar KL, Hyder F, Sze A, Shulman RG, Rothman DL (2002) Nicotine increases the rate of glutamate-glutamine cycling and glucose oxidation in rat brain in vivo. American College of Neuropsychopharmacology, San Juan, Puerto Rocio, December 7-13th. Mathalon, D.H., and Ford, J.M. (2002). The long and the short of it: Influence of interstimulus interval on auditory P300 abnormalities in schizophrenia. Clinical EEG, 33(3), 125-135. Mathalon, D.H., Pfefferbaum, A., Lim, K.O., Rosenbloom, M.J., Sullivan, E.V. (2003). Compounded brain volume deficits in schizophrenia-alcoholism comorbidity. Archives of General Psychiatry, 60, 245-252. McClung, C.A. and Nestler, E.J. (2003) Regulation of gene expression and cocaine reward by CREB and ?FosB. Nature Neurosci. 11:1208-1215. Morgan CA III, Krystal JH, Southwick SM. Toward early post-stress pharmacotherapeutic intervention. Biol Psychiatry in press. Nellissery M, Feinn RS, Covault J, Gelernter J, Anton RF, Pettinati H,
Moak D, Mueller T, and Kranzler HR: Alleles of a Functional Serotonin
Transporter Promoter Polymorphism Are Associated With Major Depression
in Alcoholics. In press, Alcohol: Clinical and Experimental Research Nich C, McCance-Katz EF, Petrakis IL, Cubells JF, Rounsaville BJ. Sex Differences in Cocaine Dependent Individual's Response to Disulfiram Treatment, Addictive Behaviors, in press. Oslin DW, Berrettini W, Kranzler HR, Pettinati H, Gelernter J, Volpicelli JR, and O'Brien CP: A fu nctional polymorphism of the µ-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients. Neuropsychopharmacology. 28(8):1546 52, 2003 Owens, J.C., Balogh, S.A., McClure-Begley, T.D., Labarca, C., Lester, H.A., Picciotto, M.R., Wehner, J.M. and Collins, A.C. (2003) a4b2*-type neuronal nicotinic receptors modulate the effects of nicotine and ethanol on the acoustic startle response. Alc Clin Exp Res, 27(12):1867-75. Peakman, M.C., Colby, C., Perrotti, L.I., Tekumalla, P., Carle, T., Ulery, P., Chao, J., Duman, C., Steffen, C., Monteggia, L., Allen, M.R., Stock, J.L., Duman, R.S., McNeish, J.D., Barrot, M., Self, D.W., Nestler, E.J., and Schaeffer, E. (2003) Inducible, brain region specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine. Brain Res. 970:73-86. Petrakis IL, Naltrexone and/or Disulfiram for Alcohol Dependent Veterans with Comorbid Mental Disorders. Alc Clin Exp Res 2003; 27(5); 176A (#81) Petrakis IL, Trevisan L, O'Malley S, Vuppalapati D, Hould J, Limoncelli D, Krystal J. Gelatin "shots", an Alternative Method of Alcohol Administration in the Laboratory. Alc Clin Exp Res 2003; 27(5); 157A (#908) Petrakis IL, Buonopane A, O'Malley S, Cermik O, Trevisan L, Boutros NN, Limoncelli D, Krystal JH. The effect of tryptophan depletion on alcohol self-administration in non-treatment seeking alcoholic individuals. Alc Clin Exp Res 2002;26(7):969-975 Petrakis IL, Gonzalez-Haddad G, Rosenheck R, Krystal JH. Comorbidity of alcoholism and psychiatric disorders. Alcohol Research and Health 2002;26:81-89 Petrakis IL, Leslie D, Rosenheck R, The use of antidepressants in alcohol dependent veterans, Journal of Clinical Psychiatry, 2003; 64(8): 865-870. Petrakis IL, O'Malley S, Rounsaville B, Poling J, McHugh-Strong C, Krystal
JH. Naltrexone augmentation of neuroleptic in alcohol-abusing schizophrenic
patients. Psychopharmacology in press Potenza, M.N., Brodkin, E.S., Luo, X.G., Remmers, EF, Nestler, E.J., and Gelernter, J. (2003) Genomic regions controlling corticosterone levels in rats. Biol. Psychiatry, in press. Potenza MN, Xian H, Shah KR, Scherrer JF, Eisen SA Shared genetic contributions to pathological gambling and major depression in men. Arch Gen Psychiatry (in press). Rosenheck R, Krystal JH, Cramer J, and VA Naltrexone Study Group 425. Effect of low and high participation in counseling on drinking cessation. Alc Clin Exp Res 2002;26(5):129A (#745) Schütz CG, Mayer C, Koller G, Wernicke M, Gueorguieva R, Krystal JH. Combining naltrexone and memantine to block the rewarding effects of alcohol-an experimental pilot study in human subjects. Alc Clin Exp Res 2002;26(5):130A (#750) Skolnick P, Krystal JH. Depression. In: Therapeutic potential of glutamate receptor antagonists and modulators. D. Lodge, W. Danysz, C.G. Parsons (Eds.). F.P. Graham and Company: Johnson, TN, 2002;71-90 Sofuoglu M, Singha A, Kosten TR,, McCance-Katz FE, Petrakis IL, Oliveto A. Effects of naltrexone and isradipine, alone or in combination, on cocaine responses in humans. Pharmacology Biochemistry and Behavior, 2003; 75: 801-808. Staley JK, Gottschalk PC, Petrakis I, Zoghbi S, Verhoeff NP, Seibyl JP,
Van Dyck C, Innis RB, Krystal JH. Cortical GABA-A receptors and the recovery
from alcohol dependence: relationship to clinical features of alcohol
dependence and cigarette smoking. In review. Staley JK, Mason G, Gottschalk PC, Petrakis I, Zoghbi S, Verhoeff NP, Seibyl JP, Van Dyck C, Innis RB, Baldwin RM, Krystal JH (2002) GABAergic dysfunction in recovering alcoholics. Proceeedings of the German Society of Addiction Research Therapy, Berlin, Germany, April 2002 Staley JK, Mason G, Petrakis I, Zoghbi SS, Verhoeff NP, Seibyl JP, Van Dyck C, Innis RB, Baldwin RM, Krystal JH (2002) Assessment of cortical GABA fuynction in acutely (< 7 days) detoxified alcohol dependent subjects. Society of Nuclear Medicine, Los Angeles, CA, June 2002 Staley JK, Petrakis I, Gottschalk PC, Ruff E, Frohlich E, Weinzimmer D, Seibyl JP, VanDyck C, Baldwin RM, Krystal JH. Iomazenil SPECT Imaging Demonstrates No Change in Cortical Benzodiazepine GABA-A Receptors in Long Term Sober Alcoholics. Alc Clin Exp Res 2003; 27(5); 20A (#90) Staley JK, Petrakis I, Gottschalk PC, Zoghbi S, Verhoeff NP, Seibyl JP,
Vandyck C, Innis RB, Baldwin RM, Krystal JH. Alterations in GABA-A receptor
binding in ethanol dependence: clinical correlates. Soc Neurosci Abstr
2002;28:899.12 Stein MB , Schork MJ, and Gelernter J: A polymorphism of the β1-adrenergic receptor is associated with low extraversion. Biological Psychiatry 2004;56:217-224 van Dyck, C. H., Malison, R. T., Staley, J. K., Jacobsen, L. K., Seibyl, J. P., Laruelle, M., Baldwin, R. M., Innis, R. B., & Gelernter, J. (in press). Central serotonin transporter availability measured with [123I]ß CIT SPECT in relation to serotonin transporter genotype. Am. J. Psychiat (in press) Waterhouse R, Slifstein M, Dumont F, Sultana A, Balter AI, Sudo Y, Laruelle M: In vivo evaluation of [11C]n-(2-chloro-5-thiomethylphenyl)-n'-(3-methoxy-phenyl)-n'-methylguanidine ([11C]GMOM) as a potential PET radiotracer for the PCP/MNDA receptor. Submitted 2004 Yang BZ, Zhao H, Kranzler HR, Gelernter J: Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE. Genetic Epidemiology 2005;25:1-11; DOI: 10.1002/gepi.20070
|
||||||||||||
|
