Heping Zhang, Ph.D.
Professor
Biostatistics
Laboratory Web page
Professor Zhang and members in his center conduct research in both the general area of regression and classification analyses and the methodologies for post-genome data analyses. In particular, with funding from multiple National Institutes of Health (NIH) grants, his group has been developing and implementing flexible and powerful approaches to the analyses of complex data including longitudinal data with multi- dimensional responses, neuroimaging data, genetic and genomic data. Zhang also has made major research efforts in: (a) child health ranging from the identification of neurological and genetic pathways in developing brain to the assessment of risk factors for pregnancy outcomes and to the understanding of cognitive and behavioral development in children; and (b) substance use, especially in understanding the transition from use to abuse. In addition, Dr. Zhang serves as Principal Investigator of the National Genomic and Proteomic Network for Preterm Birth Research.
Education
Ph.D., Stanford University, 1991
Awards and Honors
Fellow, Institute of Mathematical Statistics, 2006
Independent Scientist Award, NIH/National Institute on Drug Abuse (NIDA), 2004
Fellow, American Statistical Association, 2000
Elected Member, International Statistical Institute, 1995
FIRST Award, National Institute of Child Health and Human Development, 1994-2002
Professional Services
Associate Editor, Statistica Sinica, 2005-present
Deputy Head, Academic Committee, Center for Statistical Research, Chinese Academy of Sciences, 2005
Member, Behavioral Genetics and epidemiology Study Section (BGES), NIH, 2004
Editor, Series in Biostatistics, World Scientific Publisher Co., Inc., 2001-present
Associate Editor, Biometrics, 2000-present
Courses Taught
BIS 625b Categorical Data Analysis
Current Research Projects
Methodological Research on Substance Use; Statistical Methods in Genetic Studies of Substance Use; Research Training in Mental Health Epidemiology; and Data Management, Statistics, and Informatics Core.
Yale Affiliations
Director, Collaborative Center for Statistics in Science (C2S2)
Child Study Center
Department of Statistics
In the News
Yale Collaborative Center for Statistics in Science Receives $12.4 Million to Advance Reproductive Medicine Research
Institute of Mathematical Statistics Names Zhang Fellow
$10 Million Grant Awarded to Support a National Genomic and Proteomic Network for Preterm Birth Research
Grants Fund Statistical Methodology Development in Biomedical Research
Selected Publications
Zhang, H.P. and Zhu, H.T. Generalized Score Test of Homogeneity for Mixed Effects Models. Annals of Statistics 34: 1545-1569, 2006.
Zhang, H.P., Wang, X., and Ye, Y. Detection of Genes for Ordinal Traits in Nuclear Families and a Unified Approach for Association Studies. Genetics 172: 693-699, 2006.
Zhang, H.P., Feng, R., and Leckman, J. Linkage Analysis of Ordinal Traits for Pedigree Data. Proceedings of the National Academy of Sciences, USA 101: 16739-16744, 2004.
Zhang, H.P. Leckman, J.F., Pauls, D.L., Tsai, C.-P., Kidd, K.K., Campos, M.R. and The Tourette Syndrome Association International Consortium for Genetics. Genome Wide Scan of Hoarding in Sibling Pairs both Diagnosed with Gilles de la Tourette Syndrome. American Journal of Human Genetics 70: 2002.
Zhang, H.P., Tsai, C.-P., Yu, C.-Y., and Bonney, G. Tree-based linkage and association analyses of asthma. Genetic Epidemiology 21: S317-S322, 2001.
Zhang, H.P., Yu, C-Y, Singer, B. and Xiong, M. Recursive Partitioning for Tumor Classification with Gene Expression Microarray Data. Proceedings of the National Academy of Sciences USA 98: 6730-6735, 2001.
Zhang, H.P. Classification Trees for Multiple Binary Responses. Journal of the American Statistical Association 93: 180-193, 1998.
Risch, N. and Zhang, H.P. Extreme discordant sib pairs for mapping quantitative trait loci in humans. Science 268: 1584-1589, 1995.
For a further list of Dr. Zhang’s publications, please see PubMed.
|
