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First African-American
graduate honored

The first African-American to graduate from the School of Medicine has been honored with a new scholarship, which once fully endowed will help recruit and support outstanding students from underrepresented groups entering public health. After his graduation in 1857, Cortlandt Van Rensselaer Creed, M.D., became a prominent New Haven physician and a Civil War surgeon. He was consulted in the shooting of President Garfield in 1881, and his forensic work in the investigation of a New Haven woman’s murder played a part in Virginia A. McConnell’s novel about Victorian New Haven, Arsenic under the Elms. The Creed/ Patton/Steele Scholarship Campaign was initiated with gifts by alumnus Robert E. Steele, M.P.H. ’71, Ph.D. ’75, and also honors Creed historian Curtis L. Patton, Ph.D., professor of epidemiology (microbiology) and public health. To date, $64,000 of the $100,000 fund goal has been raised.

 

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What’s in a name?

Physicians at medical schools around the country usually provide their services through umbrella faculty practice organizations that streamline administration, financial services, compliance programs and practice standards. Yale is no exception. But in recent years the Yale Faculty Practice, which represents the medical school’s 650 full-time clinical practitioners, has evolved into a more complex organization in order to accommodate the changing landscape of academic medicine. Reflecting this, the practice announced in March that it is changing its name to the Yale Medical Group. According to Director David J. Leffell, M.D., HS ’86, the school’s senior associate dean for clinical activity, “the words ‘faculty practice’ suggested to some people that care was delivered by interns and residents who were practicing to become physicians. The new name conveys a clear message about our academic medical group and the clinical care we provide.”

 

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Parental prospects

A national survey of 3,000 adults, one-third of them parents of young children, found a surprising lack of understanding about basic principles of child development. According to the survey, many parents spank their children although they know it doesn’t work and expect a 15-month-old to share, even though that doesn’t happen until children are at least two. “Parents seem to think development is some sort of race. It’s a dance, not a race,” says Kyle D. Pruett, M.D., a clinical professor at the Child Study Center and past president of Zero to Three, the child development advocacy and expertise organization that conducted the survey. One finding he found particularly disturbing was “the lack of understanding adults have about the enormously active absorption abilities of the very young within the first months of life, both of the good and the bad in their surrounding environment.”

 

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Caffeine study quells
tempest in a coffeepot

The caffeine in over-the-counter pain relievers won’t get you hooked, according to a review of the literature by an international committee of scientists chaired by Alvan R. Feinstein, M.D., HS ’54, Sterling Professor of Medicine and Epidemiology. Fears percolating in Europe that caffeine in analgesics such as aspirin and acetaminophen might lead to dependency had spurred groups in Germany, Austria and Switzerland to seek protective regulations. Federal drug authorities in the three countries, along with the pharmaceutical industry, assembled the committee, which reported its findings in the November issue of Clinical Pharmacology and Therapeutics.

 

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15 years later,
a surprise from Chernobyl

During the 1995-1996 academic year, Jack van Hoff, M.D., HS ’84, associate professor of pediatric oncology, took a sabbatical leave from the School of Medicine to coordinate pediatric data for a cancer registry project in Belarus, the former Soviet republic. That was where the heaviest fallout occurred outside of the immediate area surrounding the Chernobyl power station following the meltdown of one of its nuclear reactors 15 years ago this spring. Along with Clinical Professor of Medicine Nicholas Dainiak, M.D., van Hoff has since worked with the International Consortium for Research on the Health Effects of Radiation to study childhood leukemia in the region. The results have been surprising. “While the social effects on people within the area have been very significant,” says van Hoff, “the physical impact of radiation exposure has been small. There has been a remarkable increase in rates of thyroid cancer for individuals exposed as children. However, there has been no detectable effect on the rates of other cancers to date.”

 

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Race not a factor

Race did not affect the quality of psychiatric care or clinical outcomes in a study of white and African-American patients who were homeless and mentally ill. The study, reported in the October issue of Psychiatric Services, also showed that the race of case managers made no difference, said author Robert A. Rosenheck, M.D., HS ’77, professor of psychiatry and public health. The findings depart from those of other studies showing that non-whites may have less access to medical care or poorer outcomes than white patients. “It is difficult to generalize from these findings to other areas of health care,” Rosenheck said. “The kinds of people who work with the homeless are generally those who have a special commitment to fairness and social justice, so these results don’t necessarily translate elsewhere.”

 

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Endoscopic surgery is easier
to swallow

People with a common swallowing disorder can now be treated at Yale using a procedure that is markedly less invasive than the conventional surgery through the neck. The surgery is used to treat Zenker’s diverticulum, which occurs when the lining of the mucous membrane protrudes through the muscular wall just below the voice box in the high esophagus. Food easily becomes trapped in the pouch, making it difficult to swallow. Using an endoscopic procedure popularized at Duke called stapler-assisted diverticulostomy, the surgeons remove the pouch through the mouth and repair the lining with a stapler. The procedure is a breakthrough, according to Douglas A. Ross, M.D., associate professor of surgery and otolaryngology, who performs the surgery along with colleague Clarence T. Sasaki, M.D. ’66, HS ’73, the Charles W. Ohse Professor of Surgery and chief of the otolaryngology section.

 

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New take on tubal transfers

The two standard procedures for in vitro fertilization involve transfer of the embryo to either the uterus or the fallopian tube. A national database published by the Centers for Disease Control and Prevention (CDC) has supported the long-held belief that tubal transfer has a higher pregnancy success rate although it is more invasive, expensive and prone to complications. An analysis directed by Steven F. Palter, M.D., assistant professor of obstetrics and gynecology, of all previously published studies found that uterine transfers have just as great a likelihood of success as tubal transfers. Palter suggested that fertility clinics, which are required to publish their success rates, select which patients to accept or direct toward certain therapies based on their likelihood of success. That, he believes, skewed the database. His findings, presented at the American Society of Reproductive Medicine meeting, contradict statistics published by the CDC and the Society for Assisted Reproductive Technology, he believes.

 

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Shorter stays, but what
about outcomes?

Managed care has reduced the time older patients with pneumonia spend in the hospital and has led to a corresponding drop in the costs and hospital death rates associated with the illness. But according to a study by researchers at Yale and other institutions, more patients are dying in the month after they leave the hospital, and many of the discharged hospital patients are being sent to nursing homes rather than home. Thomas P. Meehan, M.D., M.P.H., assistant clinical professor of medicine, was senior author of the study, which appeared in the Archives of Internal Medicine in December. The researchers found that the rate of mortality within 30 days after discharge increased from 6.9 percent to 9.3 percent during the six-year study of pneumonia patients 65 and older who were discharged from Connecticut hospitals. During that period, fall 1991 to fall 1997, the length of stay dropped from a mean of 11-12 days to 7-8 days. Said Meehan, “We can’t continue to decrease the length of stay and not have an eye as to the consequences.”

 

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Higher risks for younger women

Women under the age of 60 face a higher risk of dying during the two years following a heart attack than do men in the same age group, according to a study by a Yale researcher and collaborators. These sex-based differences in mortality rates were independent of the severity of the heart attack and other health problems, and were found only in the under-60 group of patients, the authors wrote in the Feb. 6 issue of Annals of Internal Medicine. The women’s survival rate might have been affected more than the men’s by “behavioral, psychosocial, and social factors such as continuing to smoke, social isolation, emotional stress and depression,” said Harlan Krumholz, M.D., a co-author of the article and associate professor of internal medicine. “The next challenge is to understand why these differences exist.”

 

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A scholarly archive,
in bits and bytes

As more journals move to electronic format and more scholars access information using these online databases, serious questions have arisen about how to preserve knowledge that in some cases may exist only in digital form. To address the dilemmas of digital preservation, the Yale University Library and Elsevier Science are collaborating to create the infrastructure for a model archive for the 1,100 journals published electronically by Elsevier, the world’s largest scientific, technical and medical information provider. Their goal is to have the model infrastructure developed within two years. They have already begun studying how people use digital collections and are investigating formats for encoding content in digital form; one challenge is predicting which formats are likely to remain stable over time. The planners hope that the archive will serve as a model for other publishers.

 

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Breastfeeding reduces cancer risk

Breastfeeding for two or more years reduces a woman’s risk of developing breast cancer by 50 percent, according to a study conducted in China by a Yale researcher. Tongzhang Zheng, Sc.D., associate professor of epidemiology and public health, said he conducted the study in China because, unlike in Western nations, long-term breastfeeding is part of the Chinese culture. Zheng’s group found a 50 percent reduction in breast cancer risk among women who had breastfed for more than 24 months per child, compared to women who breastfed for less than 12 months. Studies in Western countries showing that breastfeeding does not play a significant role in reducing breast cancer risk might be explained by the fact that many women in the West breastfeed for weeks or months rather than years. The study was published in the Dec. 15 issue of American Journal of Epidemiology.


Also in Et cetera:

First African-American graduate  |  What’s in a name?  |  Parental prospects  |  Tempest in a coffeepot  |  A surprise from Chernobyl  |  Race not a factor  |  Surgery easier to swallow  |  Tubal transfers  |  Shorter stays, but what about outcomes?  |  Higher risks for younger women  |  A scholarly archive  |  Breastfeeding reduces cancer risk

Chronicle  |  Rounds  |  Findings


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Originally published in Yale Medicine, Spring 2001.
Copyright © 2001 Yale University School of Medicine. All rights reserved.