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Preparing schools for the worst-case
scenario
More room to work in new anatomy
lab
Preparing for a new Step 2
For interns, a place to eat pizza
and unload stress
Honoring an NMR pioneer
Et cetera
Late neuroscientist honored
Chagas drug licensed to nonprofit

 
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Preparing schools for
the worst-case scenario
A Yale pediatrician trains educators in New York and around the world
to help children cope with crisis.
In a hotel conference room last April in New York, Yale pediatrician
David J. Schonfeld, M.D., guided 100 school counselors, teachers and administrators
through a hypothetical school crisis: the star of a high school play has
died of cancer, and classmates hold a fund-raiser in her memory to benefit
medical research. When a television news team covers the event, they learn
that a second student had died of the same form of cancer. They also report
that toxic substances have been found in the soil around the school.

The next day half the student body is absent, and the school is surrounded
by reporters; finally, the principal says that she has been diagnosed
with another form of cancer.

Working in teams, Schonfeld’s audience had to respond to each stage
of the crisis. They discussed how to determine whether there were any
health risks to students and staff; what to tell staff, students, parents
and the press; and how to support the students, the principal and other
staff. The teams had 10 minutes to spring into action, the same deadline
many New York City educators faced on September 11, 2001.

In fact, the attacks on the World Trade Center were a major reason for
the exercise. New York City school officials had asked Schonfeld, an associate
professor of pediatrics with an appointment in the Child Study Center
who has been helping schools deal with crises for more than a decade,
to train response teams that include educators, administrators, mental
health professionals, nurses and safety personnel from the city’s
approximately 1,200 schools. Along with Scott R. Newgass, M.S.W., and
David Szydlo, M.D., Ph.D., Schonfeld provided more than 50 full-day workshops
for teams from throughout the school system. With colleagues at the National
Center for Children Exposed to Violence (NCCEV), he also developed guides
for talking about 9/11, the anthrax scares, the war in Iraq and death.

Though the participants in the cancer-scare scenario groaned with each
mounting crisis, they found the discussion instructive. Most had lived
through 9/11, when administrators had to decide whether to send children
home amid the chaos. Parents flocked to schools seeking not only their
children but also information. News spread by word of mouth, more distorted
with each telling. Teachers waited for hours with students who had no
way to get home. And educators had to explain to children why this was
happening while grappling with their own distress.

“It was hours and hours of dealing with things you never could have
anticipated,” said Janet Hughes, a Bronx high school principal.
“There were a lot of things on the school level that people were
just not prepared to deal with.”

And not only in New York. Educators around the world are thinking more
about how to help children cope with disasters, including plane crashes
and earthquakes, as well as political violence. Schonfeld has also provided
training in England, Sweden and Israel; in March 2003, he provided a series
of workshops in Osaka and Tokyo as part of the establishment of Japan’s
National Mental Support Center for School Crisis.

Ten years ago Schonfeld was running the School Crisis Prevention and Response
Initiative in New Haven, with an eye to designing a national model. Today
that model is in place as part of the NCCEV at the Yale Child Study Center.
NCCEV grew out of the Child Development-Community Policing Program established
by Steven Marans, Ph.D., the NCCEV’s director, and the late Donald
J. Cohen, M.D. ’66, who led the Child Study Center from 1983 until
his death in 2002.

Schonfeld’s model is broad enough to help guide children through
a range of events. It helps educators plan for the needs of children and
school staff at a time of crisis. It also aids schools in identifying
and addressing symptoms of emotional distress and devising memorial events
that are meaningful and healing. And the model emphasizes the importance
of letting students vent. “When comments or questions come up naturally,
if the teacher is ready for them, there can be useful discussion,”
Schonfeld said.

Schonfeld wants to bring mental health needs into the mainstream of pediatric
medicine. As the physical health of children has improved, attention in
pediatrics has shifted to developmental and behavioral concerns, a relatively
new area of specialization. Yale’s Department of Pediatrics recently
created a subsection for developmental-behavioral pediatrics, and it is
the site of one of nine fellowship programs funded in July 2003 by the
Maternal and Child Health Bureau, an agency of the Department of Health
and Human Services, for training in the emerging discipline.

In November 2002, the American Board of Pediatrics offered the first exam
for certification in the field, but Schonfeld wasn’t immediately
eligible to take it, despite his obvious familiarity with the topic. He,
along with other members of the subspecialty board, had to take a different
test—one that they hadn’t written themselves.

Anne Thompson

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William Stewart, chief of the anatomy section, works with first-year students,
from left, Krishan Soni, Michael Martinez, Aida Kuri and Danielle Guez,
as they make their first incision into a cadaver.

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In gleaming anatomy
lab, more room to work and a new way of teaching
When the 100 students of the Class of 2007 donned their scrubs and rubber
gloves on September 5, they became the first group to study anatomy in
the new labs at the Anlyan Center for Medical Research and Education.
As first-timers they had no point of comparison for the brand-new, shining,
stainless steel facilities. But to anyone who has ever set foot in the
old dissection rooms, one change was obvious.

“I’m working without a mask,” said Lawrence J. Rizzolo,
Ph.D., associate professor of surgery and course director. He was, of
course, referring to the strong odor of formaldehyde—or lack of
it—in the new lab. Each station has a vent that draws odors out,
and that drew a word of caution from William B. Stewart, Ph.D., associate
professor of surgery and chief of the anatomy section. “The last
thing you ask yourself is, ‘Did I turn the vent off?’ Because
if the vent is on 24 hours a day, your cadaver will be sucked dry,”
he said.

Rizzolo delighted in another difference—more space. “I can
walk between tables,” he said.

The extra space and absence of strong odors are more than mere creature
comforts. They’ve led to a change in the study of anatomy. “Students
often come back to work extra hours,” Rizzolo said. “In the
old lab your eyes would get itchy and your throat would get scratchy.
The odor made you sick to your stomach if you stayed a long time.”

The tables are bigger and there are more of them—40 as opposed to
32. That means each dissecting station has four instead of five students.
(Although only 25 tables are needed for medical students, others are used
by the Physician Associate Program, residency programs and other institutions,
such as Quinnipiac University, which don’t have their own anatomy
facilities.) Computer terminals, which were being installed at each station
during the fall, will allow students to refer to online resources while
they are dissecting. “If a question comes up at the dissection table,
the instructor can just say, ‘Let’s look at the computer resource,’
and make a point you can’t make if the computers are 10 steps away,”
Rizzolo said.

Perhaps the biggest change for the first-year anatomy course has been
the creation of what the faculty call “learning societies”
within the class. Each is made up of 20 students and a mentor. “The
idea is for these groups to develop a sense of community and share each
other’s work,” Rizzolo said. “In the old labs, where
everyone was standing on top of one another and it was hard to move around
the lab, students would look at their own dissection and not look at who
was next to them. … The geography of the lab has allowed us to organize
this massive number of students into manageable groups that then become
a community.”

—John Curtis

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Clinical-skills course
prepares students for the wards and a new Step 2
Medicine became very personal for Jessica Kattan, a second-year student,
shortly after she took a patient’s history. “I figured he
probably had the flu,” Kattan said. But tests revealed Burkitt’s
lymphoma, a rare and aggressive form of cancer.

“The next time I saw him, he was very ill from his chemo,”
Kattan remembered. “Before that, this disease had just been some
words in a book to me.”

Kattan’s experience was part of the “Doctor-Patient Encounter.”
Now called the “Preclinical Clerkship,” it is a two-year course
aimed at teaching skills that students will need to care for patients
when they begin their clinical rotations. Margaret J. Bia, M.D., who has
directed the course since 1999, sums up its content as the heart of “doctoring”—sensitive
interactions with patients, thoughtful diagnoses and effective treatment
plans.

For the past five years, Yale students have had their history and physical
exam skills assessed at the nearby University of Connecticut assessment
center at the end of their second year. This year, students are returning
to the center at the end of their third year for an assessment of history
and physical exam skills.

Students will also have to demonstrate their mastery of these skills on
a new national exam that all medical students must pass in order to obtain
a medical license. The exam, a new, second component of Step 2 of the
United States Medical Licensing Exam (USMLE), will be required of all
medical students graduating in 2005.

This emphasis on skills assessment is part of a national movement recognizing
the importance of clinical skills in medical training and clinical care.
According to a Harris Poll, two-thirds of Americans support the new national
exam, a one-day test that strives to replicate a typical doctor’s
work day. Students will examine 10 standardized patients—actors
feigning symptoms and ailments—and formulate diagnoses and treatment
plans.

The board that oversees the USMLE sees this as a matter of public safety,
since good clinical and communication skills correlate with a lower incidence
of malpractice suits, better treatment compliance and greater patient
satisfaction. Slightly more than half of the medical schools in the United
States now require a clinical-skills exam before graduation, yet a survey
by the USMLE found that 4 percent of medical students had never taken
a history or conducted a physical under the tutelage of a faculty member.

The exam is meeting resistance from the American Medical Student Association,
because it will increase students’ debt burdens by $975, the cost
of the exam, plus expenses to travel to testing sites—Philadelphia,
Atlanta, Chicago, Los Angeles and Houston.

The new exam reflects a change from times past, when students picked up
their clinical skills in large part by observing physicians. “Now
we have 20-minute clinic visits, which markedly reduces the available
time for students to practice and receive feedback,” Bia said.

The “Preclinical Clerkship,” taken in the first two years
of medical school, fills that gap with weekly sessions that emphasize
history taking and physical examinations. Students work with faculty to
develop specific skills and meet weekly with clinical tutors who observe
them taking histories and performing physical exams. Students learn communication
skills—history taking, social history taking, breaking difficult
news—in workshops where they practice on standardized patients before
seeing real patients.

“Hopefully these developments in clinical-skills acquisition and
assessment will lead to students graduating with a greater mastery of
the skills they need to be compassionate, competent physicians,”
Bia said.

Colleen Shaddox

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Robert Shulman |
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Honoring an NMR pioneer
A June symposium, “From Molecules to Mind: Celebrating the Contributions
of Robert G. Shulman to Biological NMR,” honored Robert G. Shulman,
Ph.D., Sterling Professor Emeritus of Molecular Biophysics and Biochemistry,
for his use of nuclear magnetic resonance (NMR) to study metabolic pathways
in live subjects. Shulman, a pioneer in magnetic resonance research, has
used high-field NMR spectroscopy to follow chemical reactions and brain
activity and to develop methods for localizing brain function. The symposium
drew researchers and colleagues from around the world.

—John Curtis

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For interns, a place
to eat pizza and unload the stress of a frenetic first year
“Do I know enough to care for this patient?” “I feel
so out of touch with the rest of the world.”

These thoughts are likely to pass through the mind of the typical intern
during the first year of residency, a whirlwind time that has a component
of self-doubt accompanying rapid learning and maturation. In the past,
interns kept such worries to themselves. But at the Waterbury Hospital
Health Center, 20 miles north of New Haven, first-year residents gather
at noon each Friday to compare notes on the challenges and rigors of training.

The lunchtime talkfest is led by Seth R. Segall, Ph.D., director of psychology
at Waterbury Hospital, and Auguste H. Fortin VI, M.D., M.P.H., director
of the psychosocial curriculum at Yale’s Primary Care Residency
Program. Fortin, who said he was “concerned that the house staff
didn’t have a forum to share the feelings and the stresses of being
an intern,” began holding the weekly meetings with Segall three
years ago.

What is said in the room stays in the room. Over pizza and Pepsi, the
interns talk about the issues that affect them on the ward—the death
of a patient, the fear of an accidental needle stick, the grueling schedule
that can lead to marital stress. “This is not a regular life,”
said intern Juanita Smith, M.D., “so if you have other people around
you who say, ‘Yes I feel that too,’ it makes you realize that
your feelings are normal for the context that you are in.”

Segall starts each session with a few moments of meditation. “We’re
training physicians to listen to themselves,” he said, “and
I think that will help them to be more compassionate doctors.” Fortin
would like to expand the program to Yale’s other primary care residency
training hospitals, St. Mary’s in Waterbury and Yale-New Haven.

—Lisa Quirindongo

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Et cetera
Late neuroscientist honored
In recognition of her pioneering work on the brain’s frontal lobe
and her studies of the cerebral cortex and its links to schizophrenia,
the National Alliance for Research on Schizophrenia and Depression (NARSAD)
has created a prize to honor Patricia S. Goldman-Rakic, Ph.D., who died
in July after being struck by a car. And in November, Pfizer announced
that it will fund a graduate fellowship in neuroscience in honor of Goldman-Rakic,
the Eugene Higgins Professor of Neurobiology. Each year, an outstanding
graduate student in the Combined Program in Biological and Biomedical
Sciences will receive full support for a year’s study.

NARSAD announced The Dr. Patricia S. Goldman-Rakic Memorial Prize for
Cognitive Achievement in Neuroscience in October. The annual $40,000 prize
will reward “excellence in neurobiological research at the cellular,
physiological, or behavioral levels that may lead to a greater understanding
of major psychiatric disease.”

The first recipient of the award is Solomon H. Snyder, M.D., chair of
neuroscience at Johns Hopkins and a longtime friend and collaborator of
Goldman-Rakic. Snyder discovered the role nitric oxides play as a class
of neurotransmitter in the brain and created techniques for understanding
and manipulating brain receptors.

John Curtis


Chagas drug licensed to nonprofit
The nation’s first nonprofit pharmaceutical company has licensed
a new class of compounds from Yale and the University of Washington that
could lead to treatments for the parasitic Chagas disease, which affects
between 16 and 18 million people, mostly in Latin America.

The compounds, called azoles, were developed by teams led by Andrew D.
Hamilton, Ph.D., deputy provost for science and technology at Yale, in
collaboration with faculty at the University of Washington. Azoles inhibit
production of a chemical that is necessary for the survival of the parasite
Trypanosoma cruzi without harming human cells.

The Institute for OneWorld Health in San Francisco will have exclusive
license to develop azole compounds.

John Curtis


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