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Yale University
School of Medicine
333 Cedar Street
New Haven, CT 06510
Office of
Student Research
367 Cedar Street
Room 310 ESH
New Haven, CT 06510
Office: (203) 785-6633
Fax: (203) 785-6936
EMAIL US
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INTENSIVE
PEDAGOGICAL EXPERIENCE
Click for
Slide
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TO: Yale Medical Students, Class of 2009
FROM: Robert J. Alpern, M.D., Dean
RE: Intensive Pedagogical Experience Course
On behalf of the School
of Medicine it is a pleasure to welcome you to this elective
course, now into its seventh year, an Intensive Pedagogical
Experience (IPE) in Laboratory Research Techniques, organized
by Drs. Forrest, Forbush and Frizzell at the MDI Biological
Laboratory.
I feel strongly that
every physician graduate at Yale should have first-hand,
in-depth understanding of contemporary experimental
approaches to solving important questions in biomedical
research.
A complete intensive
immersion in the strategies and methods of laboratory
research is the most direct way to begin this experience.
A one-week intensive course, energized, focused and
effective, is a first step towards the in-depth training
required to carry out biomedical research in today’s
environment.
We hope that this immersion
course will stimulate your curiosity and encourage you
to receive further biomedical research training, perhaps
through a one-year funded student research fellowship,
and will motivate you towards the noble and rewarding
goals of a physician scientist. |
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| IPE
Rotation Schedule and Assignments |
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Rotation A includes:
Physiological studies of chloride transport in an intact
epithelial organ: In vitro cannulation and perfusion
of shark salt gland, measurements of hormone activation
of NaCl secretion.
Rotation B includes: Ion channel
gene expression in a heterologous expression system
(Xenopus ocytes). Isolation of oocytes, cRNA preparation,
oocyte injection, record channel function (CFTR and
EnaC).
Rotation C includes: Studies in
isolated tubule preparations, including immunocytochemistry
of phosphoryated vs non-phosphorylated co-transporters:
tissue processing, confocal microscopy, Western blots,
antibody design.
Rotation D includes: Molecular
biology of membrane proteins and transporters in shark
salt gland: RNA, cDNA, PCR, cloning, sequencing.
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| IPE
Tentative Rotation Schedule and Assignments |
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Saturday
June 10 |
| Arrival |
Access
to Residence Halls after 3:00 PM
Afternoon Free! |
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| 8:00
PM |
Barbecue – Co-op
Dining Hall Lawn
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| 9:00
PM |
All Groups –
Orientation and Opening Talk,
Introduction of Labs Rotations, Maren Auditorium,
MDIBL |
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Sunday
June 11 |
8:30 AM, PM and Evening: Rotations A1, B1,
C1, D1 |
Monday
June 12 |
| 8:30
AM |
Rotations A1,
B1, C1, D1 |
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| 10:00
AM |
All Groups –
Small Lab Meetings (by Rotation) |
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| 12:00
PM |
Lunch |
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| 12:30
PM |
Large Lab Meeting |
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| 2:30
PM |
Free Time |
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Tuesday
June 13 |
8:30 AM, PM & Evening: Rotations A2,
B2, C2, D2 |
Wednesday
June 14 |
| 8:30
AM |
Rotations A2,
B2, C2, D2 |
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| 10:00
AM |
All Groups –
Small Lab Meetings (by Rotation) |
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| 12:00
PM |
Lunch |
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| 12:30
PM |
Large Lab Meeting |
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| 2:30
PM |
Free Time |
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| 7:30
PM |
LECTURE
TBA |
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Thursday
June 15 |
8:30
AM, PM and Evening: Rotations A3, B3, C3, D3
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Friday
June 16 |
| 8:30
AM |
Rotations A3, B3, C3, D3 |
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| 10:00
AM |
All Groups – Small Lab Meetings (by Rotation) |
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| 12:00
PM |
Lunch |
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| 12:30
PM |
Large Lab Meeting and Evaluation |
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| 2:30
PM |
Free Time |
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| 7:00
PM |
Lobster Fest at Seawall – Acadia National
Park! |
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Saturday
June 17 |
Depart
by 11:00 AM |
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