Acute Coronary Syndrome

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Prognosis of Patients with Acute Coronary Syndrome

Despite the use of aspirin, heparin and anti-ischemic therapy, modern clinical trials have documented that the prognosis of patients presenting with an acute coronary syndrome remains poor. Within 4 to 6 weeks of presentation, the risk of death or myocardial infarction is 8% to 14%. (Table 1). The rate of death, MI, or refractory ischemia is even more excessive (approximately 15% to 25%) [1].

Fig. 1. Prognosis of patients with acute coronary syndrome treated with “conventional therapy.”

*Placebo arms (aspirin, heparin monotherapy, and anti-ischemic treatment) of PRISM and PRISM-Plus.

*Approximately 1 out of 10 patients presenting with an acute coronary syndrome will either die or sustain a myocardial infarction within 4 to 6 weeks of presentation.


1. Theroux P., Fuster, V. Acute coronary syndrome. Unstable angina and non-Q-wave myocardial infarction. Circulation 1998; 97:1195-1206.

Last modified: October 14, 1999 (PL)

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