Sofia Simona Jakab, M.D.

Assistant Professor
Section of Digestive Diseases

more on this physician

Clinical Interests

Dr. Jakab is involved in multiple aspects of the clinical practice within the Section of Digestive Diseases and Yale New Haven Transplantation Center. Her clinical interests include evaluation and treatment of patients with hepatitis B, C, fatty liver disease, drug-induced liver disease, cirrhosis, as well as management of patients before and after liver transplantation. She also performs liver biopsy, large volume paracentesis, endoscopic evaluation and treatment of esophageal varices, colonoscopy for colorectal cancer screening, and general endoscopic evaluation of the upper and lower gastrointestinal tract. Dr. Jakab serves as attending hepatologist and attending transplant hepatologist at Yale New Haven Hospital.

Research Interests

Her research interests are focused on treatment of hepatitis B, C, fatty liver disease, medical residents’ education in the management of liver diseases, and living-donor liver transplantation. During her advanced training in hepatology/liver transplantation at Thomas Jefferson Hospital, she conducted research in HLA matching for living-donor liver transplantation and molecular pathogenesis of hepatocellular carcinoma.

Education and Training

Dr. Jakab is a graduate of the Timisoara University of Medicine in Romania. Her internship and residency in Internal Medicine, as well as her gastroenterology fellowship training were completed at Norwalk Hospital, Norwalk, CT, programs affiliated with Yale University. She did elective rotations at the Center for Liver Disease and Transplantation, Columbia-Presbyterian Hospital, and the Department of Liver Transplantation and Hepatobiliary Surgery, Lahey Clinic. She received advanced training in Hepatology and Liver Transplantation at Thomas Jefferson University Hospital/Jefferson Medical College.

Selected Publications

• Jakab SS, Navarro VJ, Colombe BW, Daskalakis C, Herrine SK, Rossi S. The Impact of HLA Match on Living-Donor Liver Transplantation Outcomes: An Analysis of the United Network for Organ Sharing Database. Liver Transplantation. 2007 Oct;13(10): 1405-13.
• Jakab SS, West AB, Meighan DM, Brown RS Jr, Hale WB. Mycophenolate Mofetil for Drug-Induced Vanishing Bile Duct Syndrome. World J Gastroenterol. 2007 Dec 7;13(45):6087-9.
• Jakab SS, Mitroo P, Rubin R, Herrine SK, Navarro VJ. Extensive Intrahepatic Cholelithiasis with Large Biliary Abscesses. Poster presentation, ACG National Fellows Forum, Reston, VA, June 2006.
• Jakab SS, Clayton M, Herrine SK, Navarro VJ, Feitelson M. Expression of HBx-Regulated Genes Is Not Limited To HBV-Related Hepatocellular Carcinoma. Oral presentation, Komarov Competition, Philadelphia, March 2006.
• Gaglio PJ, Jakab SS, Novogrudsky A, Emond JC, Lefkowitch J, Brown RS Jr. Hepatitis C Recurrence Following Liver Transplantation: Does Histologic Severity of Inflammation in the Explant Correlate with Recurrence? Poster presentation, 2004 American Transplant Congress, Boston, MA.

Contact

Office Address
Temple Medical Center
Yale Digestive Diseases
40 Temple Street, Suite 1A
New Haven, CT 06510

E-mail
simona.jakab@yale.edu

Office
Phone (203) 737-2716

Hepatology Appointments
Phone (203) 785-4138
Fax (203) 737-1345

Liver Transplantation Appointments
Phone (203) 785-2565
Fax (203) 785-7617