Cyrus R. Kapadia, M.D.

Professor of Medicine
Director of Residency Program
Section of Digestive Diseases
more on this physician

Research Interests

I have focused on two areas related to clinical aspects of colorectal cancer. The first are epidemiological studies that test the role of screening programs for the prevention of colon cancer or evaluate the role of surveillance after surgery. A prospective study of colonoscopy as a primary screening modality and a retrolective cohort study of the use of colonoscopy in patients operated on for colon or rectal cancer are underway.

The second area of study uses the technique of laser-induced fluorescence spectroscopy during colonoscopy to enable the discrimination of normal mucosa from premalignant lesions in the colon. This discrimination is achieved in real time by an on-line computer analysis of replicate laser-induced fluorescence spectra derived from the target tissue. Tissue type is determined based on algorithms derived from fluorescence spectra previously obtained from normal and pathological tissue.

Clinical Interests

General gastroenterology with emphasis on gastrointestinal malignancies, ulcer disease, and malabsorptive states.

Selected Publications

• Fiarman GS, Nathanson MH, West AB, Deckelbaum Ll, Kelly L, Kapadia CR. Differences in laser-induced autofluorescence between adenomatous and hyperplastic polyps and normal colonic mucosa by confocal microscopy. Digestive Diseases and Sci, 40: (in press)
• Kapadia, C.R., Spiro, H. Gastroenterology. Of oxides and onions. Lancet 348(2):S117, 1996.
• Kapadia, C.R. Vitamin B12 deficiency after gastric surgery: Its early detection. Gastro 111:1151-2, 1996.
• Kapadia, C.R. Fibrosing colonpathy in cystic fibrosis: Results of a case-control study. Gastro 111:260-1, 1996.