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Cover:
The chemotactic migration of leukocytes toward an inflammation site
involves a complex set of interactions between several cell types (neutrophils,
adjacent cells, and bacteria) and several mediators (combinations of chemoattractant
gradients). Chemoattractants are released by endothelial cells, by activated
stromal cells (macrophages, epithelial cells), and by the inflammatory targets,
ie, bacteria or dying cells. The direction of neutrophil movement is first
guided by the steepest local chemoattractant gradient and is then regulated
by successive receptor desensitization and attraction by secondary distant
agonists. See article by Witko-Sarsat et al. |
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- Dissociation of Inflammatory and Epithelial
Responses in a Murine Model of Chronic Asthma Paul
S. Foster, Yang Ming, Klaus I. Matthei, Ian G. Young, Jason Temelkovski,
and Rakesh K. Kumar
- Association of Mycobacterium leprae with Human
Endothelial Cells In Vitro David
M. Scollard
- Ceramide Induces Cell Death in the Human Prostatic
Carcinoma Cell Lines PC3 and DU145 but Does Not Seem to Be Involved
in Fas-Mediated Apoptosis Andreas
Gewies, Oskar W. Rokhlin, and Michael B. Cohen
- Expression and Tissue Localization of Membrane-Types
1, 2, and 3 Matrix Metalloproteinases in Rheumatoid Synovium
Hajime Yamanaka, Ken-ichi Makino, Masayuki Takizawa, Hiroyuki Nakamura,
Noboru Fujimoto,Hideshige Moriya, Ryoichi Nemori, Hiroshi Sato, Motoharu
Seiki, and Yasunori Okada
- Correlation of p16 Hypermethylation with p16
Protein Loss in Sporadic Gastric Carcinomas Yhong-Hee
Shim, Gyeong Hoon Kang, and Jae Y. Ro
- PDGF-Mediated Chemoattraction of Hepatic Stellate
Cells by Bile Duct Segments in Cholestatic Liver Injury
Nils Kinnman, Rolf Hultcrantz, Véronique Barbu, Colette Rey,
Dominique Wendum, Raoul Poupon, and Chantal Housset
- Clonality and Genetic Divergence in Multifocal
Low-Grade Superficial Urothelial Carcinoma as Determined by Chromosome
9 and p53 Deletion Analysis
Arndt Hartmann, Ursula Rösner, Gudrun Schlake, Wolfgang Dietmaier,
Dirk Zaak, Ferdinand Hofstaedter, and Ruth Knuechel
- Plasma Escherichia coli [beta]-Galactosidase
as a Marker of Tumor Burden and Response to Experimental Anti-Neoplastic
Therapy in Nude Mice Xenografted with lacZTransduced Human Tumor Cells
Claus Holst-Hansen, Ross Wentworth Stephens, Bente Egholm Johannessen,
Peter Buhl Jensen and Nils Brüner
- Induction of Chromosomal Aberrations and Growth-Transformation
of Lymphoblastoid Cell Lines by Inhibition of Reactive Oxygen Species-Induced
Apoptosis with Interleukin-6
Hideaki Miwa, Hiroyuki Kanno, Satoru Munakata, Yumiko Akano, Masafumi
Taniwaki, and Katsuyuki Aozasa
- Replenishment of Glutathione Levels Improves
Mucosal Function in Experimental Acute Colitis
Esther Ardite, Miguel Sans, Juliá Panés, Francisco J.
Romero, Josep M. Piqué, and José C. Fernández-Checa
- Metallothionein Inhibits Myocardial Apoptosis
in Copper-Deficient Mice: Role of Atrial Natriuretic Peptide
Y. James Kang, Zhan-Xiang Zhou, Huiyun Wu, Guang-Wu Wang, Jack T. Saari,
and Jon B. Klein
- Protective Role of Interleukin-1 in Mycobacterial
Infection in IL-1 [alpha]/[beta] Double-Knockout Mice
Hiroyuki Yamada, Satoru Mizumo, Reiko Horai, Yoichiro Iwakura, and Isamu
Sugawara
- Islet Abnormalities Associated with an Early
Influx of Dendritic Cells and Macrophages in NOD and NODscid Mice
Judith G. M. Rosmalen, Françoise Homo-Delarche, Sylvie Durant,
Marcel Kap, Pieter J. M. Leenen, and Hemmo A. Drexhage
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Minireview featured this month |
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Neutrophils: Molecules, Functions and Pathophysiological
AspectsVeronique Witko-Sarsat,
Philippe Rieu, Beatrice Descamps-Latscha, Philippe Lesavre, and Lise Halbwachs-Mecarelli
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Initial Intermittent Microwave Irradiation for Fluorescence In Situ Hybridization
Analysis in Paraffin-Embedded Tissue Sections of Gastrointestinal NeoplasiaYasuhiko
Kitayama, Hisaki Igarashi, and Haruhiko Sugimura
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