The United States and Canadian Academy of Pathology Lippincott Williams and Wilkins publishes Laboratory Investigation

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			Cover: Kocher et al present evidence that a novel protein called PDZK1 links to a multidrug resistance gene, and, like such genes, PDZK1 is often linked to cancer. The figure shows localization of PDZK1 to human chromosome 1q21 (top), and high expression of PDZK1 in a colonic adenocarcinoma (bottom).
		MULTIDRUG RESISTANCE BY PDZK1 ON CHROMOSOME 1Q21: (Kocher, et al) SURVIVIN AND SKIN CANCER: (Grossman, et al) MORE OF THE SAME IS NOT NECESSARILY BAD: (Salanova, et al) N-ACETYLCYSTEINE: NEW ROLE FOR AN OLD DRUG: (Cai, et al)
		Microsatellite Instability and Loss of Heterozygosity in Primary and Secondary Proliferative Lesions of the Parathyroid Gland Naoki Koshiishi, Ja-Mun Chong, Tomoki Fukasawa, Rie Ikeno, Akira Tanaka, Kyotaro Kanazawa, Mitsuo Ogura, Masakazu Ebuchi, Toichiro Takizawa, Nobuaki Funata, and Masashi Fukayama Expression of an IL-1 Receptor Antagonist during Mouse Hepatocarcinogenesis Demonstrated by Differential Display Analysis Yoshihisa Yamada, Hidenori Karasaki, Kouji Matsushima, Gang-Hong Lee, and Katsuhiro Ogawa Apoptosis in Multinucleated Skeletal Muscle Myotubes Anne McArdle, Antonia Maglara, Paul Appleton, Alastair J. M. Watson, Ian Grierson, and Malcolm J. Jackson Effects of Proteasome and Calpain Inhibitors on the Structural Reorganization and Proliferation of Vascular Smooth Muscle Cells in Primary Culture Johan Thyberg and Karin Blomgren Hypoxia Induces Renal Tubular Epithelial Cell Apoptosis in Chronic Renal Disease Shenaz Khan, Ronald P. Cleveland, Cameron J. Koch, and Jeffrey R. Schelling VEGF Via VEGF Receptor\N1 (Flt\N1) Mimics Preeclamptic Plasma in Inhibiting Uterine Blood Vessel Relaxation in Pregnancy: Implications in the Pathogenesis of Preeclampsia Jeremy Brockelsby, Richard Hayman, Asif Ahmed, Averil Warren, Ian Johnson, and Philip Baker Accumulated Frameshift Mutations at Coding Nucleotide Repeats During the Progression of Gastric Carcinoma with Microsatellite Instability Jung Jin Kim, Myung Jin Baek, Lucia Kim, Nam-Gyun Kim, Yong Chan Lee, Si Young Song, Sung Hoon Noh, and Hoguen Kim Expression of the Apoptosis Inhibitor, Survivin, in Nonmelanoma Skin Cancer and Gene Targeting in a Keratinocyte Cell Line Douglas Grossman, Jennifer M. McNiff, Fengzhi Li, and Dario C. Altieri Is Hyperdiploidy of Immature Ejaculated Germ Cells Predictive of Testis Malignancy? A Comparative Study in Healthy Normozoospermic, Infertile, and Testis Tumor Suffering Subjects Michele Salanova, Loredana Gandini, Andrea Lenzi, Claudia Chiarenza, Antonio Filippini, Franco Dondero, Franco Di Silverio, and Mario Stefanini Immunohistochemical Survey of p16INK4A Expression in Normal Human Adult and Infant Tissues Gunnlaugur P. Nielsen, Anat O. Stemmer-Rachamimov, Joan Shaw, Jennifer E. Roy, Jim Koh, and David N. Louis Microsatellite Alterations in Serum DNA of Patients with Colorectal Cancer Konrad Kölble, Oliver M. Ullrich, Heiko Pidde, Beatrix Barthel, Johannes Diermann, Birgit Rudolph, Manfred Dietel, Peter M. Schlag, and Siegfried Scherneck Mutation of p53 and K-ras, and Loss of Heterozygosity of APC in Intrahepatic Cholangiocarcinoma Yun Kyung Kang, Woo Ho Kim, Hye Won Lee, Hye Kyung Lee, and Yong Il Kim Activation of Cultured Rat Hepatic Stellate Cells by Tumoral Hepatocytes Saadia Faouzi, Sébastien Lepreux, Christiane Bedin, Liliane Dubuisson, Charles Balabaud, Paulette Bioulac-Sage, Alexis Desmoulière, and Jean Rosenbaum N-Acetylcysteine Inhibits Endothelial Cell Invasion and Angiogenesis Tania Cai, GianFranco Fassina, Monica Morini, Maria Grazia Aluigi, Luciana Masiello, Gabriella Fontanini, Francesco D'Agostini, Silvio De Flora, Douglas M. Noonan and Adriana Albini PDZK1, a Novel PDZ Domain-Containing Protein Up-regulated in Carcinomas and Mapped to Chromosome 1q21, Interacts with cMOAT (MRP2), the Multidrug Resistance-Associated Protein Olivier Kocher, Natalia Comella, Annalyn Gilchrist, Rinku Pal, Kathi Tognazzi, Lawrence F. Brown, and Joan H. M. Knoll
			Recent Advances in the Molecular Basis of TNF Signal Transduction Elizabeth C. Ledgerwood, Jordan S. Pober, John R. Bradley
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