Research in our laboratory is focused on conformational changes in proteins which give rise to a special class of protein complex known as amyloid fibrils.

Morgan, C., Gelfand, M., Atreya, C. and Miranker, A. D. (2001) Kidney dialysis-associated amyloidosis: a molecular role for copper in fibril formation J. Mol. Biol. 309:339-345

Padrick, S. Miranker, A. D. (2001) Islet amyloid polypeptide: Identification of long range contacts and local order on the fibrillogenesis pathway J. Mol. Biol. 308:783-794

Larson, J. L., Ko, E. Miranker, A. D. (2000) Direct measurement of islet amyloid polypeptide fibrillogenesis by mass spectrometry Protein Science 9:427-431