IntroductionThe synchronous activity of large numbers of
neurons in the brain generates significant electric fields. These
electric fields have been previously shown to influence pathological
activity such as epileptic seizures. During slow wave sleep, the
neocortex also generates large electric fields. Here we asked
whether or not these electric fields may actively participate in the
control of neocortical activity during slow wave sleep.
Here we demonstrate that the electrical fields generated by the neocortex actually influence its activity.
This seminar is based upon a recent publication: Frohlich, F. and McCormick, D.A. (2010) Endogenous electric fields may guide neocortical network activity.
Neuron 67: 129-143.