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Diabetes Epidemic: An Uphill Battle That Can Be Won

[November, 2007] News from the diabetes front seems to grow more discouraging by the day.

Rates of the disease, fueled by obesity and sedentary lifestyles, have risen unchecked in the United States, with diabetes now affecting about seven percent of the population. That is an estimated 20.8 million adults and children, according to the American Diabetes Association (ADA).

Picture of a man on a scales and a physician scolding him

Federal projections estimate that by 2050, some 48 million Americans will have type 2 diabetes. And the disease will bring with it complications such as blindness, hearing loss, kidney disease, nervous system disorders, and amputations of extremities.

Next Generation May Not Live as Long

"Studies have suggested that for the first time in history, the generation of people born in 2000 is probably going to have shorter life expectancy than their parents," says Dr. Sue Kirkman, vice president of clinical affairs for the American Diabetes Association.

What is worse, one of the most promising medicines for treating type 2 diabetes,Avandia®, now appears to increase a person's risk of heart attack and heart failure, according to recent studies.

Still, with November designated American Diabetes Month, medical experts say the fight against diabetes can be won - if everyone decides to do what is best for themselves and their families. It will not be easy.

The finding on Avandia calls into question the safety of the entire class of drugs known as thiazolidinediones. For now, Avandia - and other thiazolidinediones such as Actos®,  - remains on the market. But in August, the US Food and Drug Administration (FDA) mandated stricter labeling, including "black box" warnings, for the medications.

A black box warning is a prominent medication-label alert for high risk prescription drugs that may cause serious injuries or death.

Medical experts recommend that each person discuss the risks and rewards of using Avandia with their physician.

"Every patient is different," states Dr. Kirkman. "Every patient has different risk factors. Every patient has reasons why one medicine might be better for them than another."

But medicines are only part of the solution. A better response would be drastic changes to American lifestyles, starting with improved diets and more exercise, to avoid type 2 diabetes in the first place.

"The statistics are pretty gloomy, but we also know people who are at risk for diabetes can do a lot to prevent it from coming on," Dr. Kirkman encourages. "There's a lot people can do to try and control their fate."

The Diabetes Epidemic

Diabetes comes in two types. The most common form, type 2, or what used to be called adult-onset diabetes, occurs when either the body does not produce enough of the hormone insulin or the cells ignore the insulin. The body needs insulin to transport sugar in the blood to cells for energy.

Being overweight, an unhealthy diet, and lack of exercise are common contributors to this form of the disease.

Type 1 diabetes, usually diagnosed in children and young adults, occurs when the body is not capable of producing insulin.

Researchers reviewing data from the National Health Interview Survey found that from 1990 to 2005, cases of diabetes increased 4.6 percent each year. They rose from 26.4 cases per 1,000 people to 54.5 per 1,000 people in the most recent year available.

The diabetes epidemic has grave implications for America, says Martha Funnell, a clinical nurse specialist for the University of Michigan and a past president of the ADA. Health care costs are expected to soar as more people with diabetes complications fill doctors' offices and emergency rooms.

Even the US economy will be affected as potentially healthy people find themselves unable to work. "You're losing folks in the prime of their years, and that has an impact on society and our economy," Funnell says.

There Is Hope

Fortunately, there are steps that can be taken, both large and small, to help fight diabetes.

On the large-scale side, Dr. Kirkman says, governments should spend more money on physical education in schools and on public transportation, instead of new road construction.

"We know people who take public transportation are more physically active," she says. "Do we choose to encourage that?"

"On a more personal level, people can make healthy lifestyle choices and help pass those choices along to their children," Funnell says. "But is anyone listening and willing to try?"

"The messages are those same old 'eat healthy and exercise,' and we hear those to the point where we think, 'Yeah, yeah, yeah, everybody knows we need to do these things," Funnell says.

Baby Steps

However, even small measures - standing more often during the day or walking during a lunch break or eating an apple instead of ice cream - can help make a difference.

"Maybe it would seem to outsiders as a small step, but it's just taking that one step and the next step and the next," Funnell says. "Like global warming, it's saying, What can I do for myself and my family this week, this month, this year, that will make a difference?"

Always consult your physician for more information.

 
 
Yale School of Medicine